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Say It Ain't Zo?: Examining the Data Behind Vancomycin/piperacillin-tazobactam Nephrotox

This presentation aims to highlight new literature evaluating nephrotoxicity associated with vancomycin and piperacillin-tazobactam combination therapy. Vancomycin and piperacillin-tazobactam is a combination that tends to be avoided due to its effect on renal function; in this presentation, we will discuss various acute kidney injury classification systems as well as the combination's effect on different markers of renal function.



CE Hours


CE Units


Activity Type

  • Knowledge


Participants have 60 days from the start of their program to claim CE credit and verify it has been upload to CPE Monitor. If your program requires the completion of a post test/eval/survey those items MUST be done before that 60 day window closes to receive credit for that program. Statements of credit can be viewed and printed from CPE Monitor. Statements of credit will no longer be printed and mailed to the participant. **No partial individual session credit will be given**
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If paying by check please mail to the address below:

UNC Eshelman School of Pharmacy
Attn: Continuing Education
301 Pharmacy Lane, CB# 7574 Beard Hall
Chapel Hill, NC 27599
Accreditation Council for Pharmacy Education
The University of North Carolina Eshelman School of Pharmacy is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. To receive CE credit, participants must complete the CE attendance form and the online evaluation of the program (instructions to be emailed). Statements of credit can be viewed and printed in CPE Monitor approximately 2 to 3 weeks after the program and you have completed any needed requirements. **No partial credit will be available**


UNC Health System





  • Describe proposed mechanisms and risk factors for vancomycin and piperacillin-tazobactam (VN+PT) nephrotoxicity
  • Differentiate between various acute kidney injury classification systems and apply to patient case
  • Discuss existing literature and current clinical practice surrounding concomitant VN+PT administration
  • Outline the nephrotoxicity risk and prevalence of VN+PT using new and upcoming data


Morgan Bizzell, PharmD
PGY1 Pharmacy Resident

Activity Number


Release Date: Oct 11, 2022
Credit Expiration Date: Oct 11, 2023

CE Hours